高西辉
职 称：青年研究员，博士生导师
电子邮箱：gaoxihui@fudan.edu.cn
办公地点：复星楼207
教育经历
工作经历
获得人才项目
获得奖项
研究方向
科研项目
课程讲授
学术兼职
代表性论著
2014.09-2017.07 复旦大学药学院 药剂学博士
2011.09-2014.07 复旦大学药学院 药剂学硕士
2006.09-2010.07 山东大学药学院 药学学士
2019.07-至今 williamhill官网，病原生物学系，青年研究员
Biomaterials Science 2021年度Emerging Investigators；
上海市青年科技启明星人才计划；
中国博士后创新人才支持计划。
上海市浦东新区优秀科技论文一等奖；
国际脑血流与脑代谢大会青年学者旅行奖，德国柏林。
抗感染、抗肿瘤药物/核酸递送载体开发；
基因/化学工程化溶瘤病毒开发。
主持国家自然科学基金面上项目、国家自然科学基金青年项目、上海市青年科技启明星、上海市重大传染病专项子任务、复旦大学引进人才项目、复旦大学争优人才培养计划、中国博士后创新人才支持计划、中国博士后基金等多项科研项目。
医学微生物学、医药中的同位素技术、细胞微生物学。
国际脑血流与脑代谢学会会员；
国际分子影像学会会员；
中国生物医学工程学会会员；
Xihui Gao#, Sha Li#, Fei Ding, Xinlong Liu, Yijing Wu, Jing Li, Jing Feng*, Xinyuan Zhu, Chuan Zhang*. Virus‐mimicking nucleic acid nanogel reprograms the microglia and macrophage for glioblastoma therapy. Adv. Mater., 2021, 33, 2006116. (IF: 30.849)
Xihui Gao#, Qi Yue#, Zining Liu, Mengjing Ke, Xingyu Zhou, Sihan Li, Jianping Zhang, Ren Zhang, Ying Mao and Cong Li*, Guiding brain tumor surgery via blood brain barrier permeable gold nanoprobes with acid triggered MRI/SERRS signal. Adv. Mater., 2017, 29, 1603917. (IF: 30.849)
Xihui Gao#, Sha Li#, Fei Ding, Hongjia Fan, Leilei Shi, Lijuan Zhu, Jing Li, Jing Feng*, Xinyuan Zhu, Chuan Zhang*, Rapid detection of exosomal microRNAs using virus-mimicking fusogenic vesicles. Angew. Chem. Int. Ed. Engl. 2019, 58, 8719-8723. (IF: 15.336)
Xihui Gao, Junqiang Ding, Chongbing Liao, Jinliang Xu, Xiaoxiao Liu, Wuyuan Lu*. Defensins: the natural peptide antibiotic. Adv. Drug Deliv. Rev., 2021: 114008. (IF: 15.470)
Leilei Shi, Wenbo Wu, Yukun Duan, Li Xu, Sha Li, Xihui Gao*, and Bin Liu*. Carrier-free hybrid DNA nanoparticles for light-induced self-delivery of functional nucleic acid enzymes. ACS Nano 2021, 15, 1841–1849. (co-corresponding author, IF: 15.881)
Xihui Gao, Jun Qian, Shuyan Zheng, Yinzhi Changyi, Jianping Zhang, Shenghong Ju*, Jianhua Zhu, Cong Li*, Overcoming the blood–brain barrier for delivering drugs into the brain by using adenosine receptor nanoagonist. ACS Nano 2014, 8, 3678-3689. (IF= 15.881)
Jiapei Yang#, Lei Wang#, Yue Su#, Lingyue Shen, Xihui Gao*, Leilei Shi*, Xinyuan Zhu*, Color-convertible fluorescent nanoprobe for Parkinson disease diagnosis. Chem. Eng. J. 2021, 33, 15, 5974–5980. (co-corresponding author, IF: 13.273)
Xihui Gao#，Qi Yue#，Yikang Liu，Dandan Fan，Kun Fan，Sihan Li，Jun Qian，Limei Han，Fang Fang, Fulin Xu, Daoying Geng, Liang Chen*, Xin Zhou, Ying Mao, and Cong Li*, Image-guided chemotherapy with specifically tuned blood brain barrier permeability in glioma margins. Theranostics 2018, 8, 3126. (IF= 11.556)
Xihui Gao#, Junqiang Ding#, Qianqian Long#, Changyou Zhan*. Virus-mimetic systems for cancer diagnosis and therapy. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol., 2021, e1692. (IF: 9.182)
Sha Li#, Jinliang Xu#, Jun Qian, Xihui Gao*. Engineering extracellular vesicles for cancer diagnosis and therapy: recent advances and challenges in clinical translation. Biomater. Sci., 2020, 8, 6978-6991. (IF: 6.843)
Huihui Yan#, Xihui Gao#, Yunfei Zhang, Wenju Chang, Jianhui Li, Xinwei Li, Qin Du, Cong Li, Imaging tiny hepatic tumor xenografts via endoglin-targeted paramagnetic/optical nanoprobe. ACS Appl. Mater. Interfaces, 2018, 10, 17047-17057. (co-first author, IF= 9.229)
Sha Li, Yijing Wu, Fei Ding, Jiapei Yang, Jing Li, Xihui Gao*, Chuan Zhang*, Jing Feng*. Engineering macrophage-derived exosomes for targeted chemotherapy of triple-negative breast cancer. Nanoscale, 2020, 12, 10854-10862. (co-corresponding author, IF: 7.790)
Han Xue, Fei Ding, Jiao Zhang, Yuanyuan Guo, Xihui Gao*, Jing Feng, Xinyuan Zhu and Chuan Zhang*. DNA tetrahedron-based nanogels for siRNA delivery and gene silencing. Chem. Commun., 2019, 55, 4222-4225. (co-corresponding author, IF= 6.222)
Xihui Gao#, Yuancheng Wang#, Yikang Liu, Qi Yue, Zining Liu, Mengjing Ke, Shengyuan Zhao, Cong Li*, Nanoagonist-mediated endothelial tight junction opening: A strategy for safely increasing brain drug delivery in mice. J. Cereb. Blood Flow Metab. 2017, 37, 1410-1424. (IF= 6.200)
