职 称:副教授
联系电话:021-54237611
电子邮箱:wenlimi@fudan.edu.cn
办公地点:上海市徐汇区东安路130号西13号楼711室
教育经历
工作经历
获得人才项目
获得奖项
研究方向
科研项目
讲授课程
学术兼职
代表性论著
代表性专利
1999.09—2004.06 新乡医学院临床医学专业本科生
2004.09—2009.06 复旦大学上海医学院中西医结合基础专业博士研究生
2009.07—2015.11 williamhill官网讲师
2013.11—2014.11 美国哈佛大学附属麻省总医院麻醉科博士后
2015.12—至今 williamhill官网副教授
2016,尚学计划,williamhill官网
2015,卓学计划,复旦大学
2009,研究学者,复旦大学上海医学院
2018,复旦大学2018年度青年教师教学竞赛(医科组)三等奖
2016,复旦大学第一三共奖教金
2016,中国中西医结合学会科学技术二等奖(第三完成人)
2015,中国神经科学会赛诺菲优秀会议论文奖
疼痛及中药、针刺、运动镇痛的神经生物学机制
瘙痒及中药、针刺止痒的神经生物学机制
2023,国家自然科学基金面上项目,IL-33调控vlPAG星形胶质细胞-GABA能神经元互作介导神经病理性冷痛的作用及机制,主持
2022,科技创新2030—脑科学与类脑研究重大项目,胶质细胞在中枢神经系统稳态和功能维持中的作用,项目骨干
2021,上海市教委高水平地方高校试点建设重点创新团队,针刺治病的神经-内分泌-免疫网络机制,参与
2019,上海市教委高水平地方高校试点建设战略创新团队, 针灸神经免疫网络及调控机理,参与
2018,国家自然科学基金面上项目,冷受体TRPM8在IL-33介导神经病理性冷痛中的作用及机制,主持
2017,上海市卫生和计划生育委员会科研课题青年项目,脊髓NALP1炎症小体在姜黄素缓解小鼠神经痛中的作用及机制,主持
2015,上海市自然科学基金,脊髓IL-33/ST2通路在慢性吗啡镇痛耐受中的作用及信号机制,主持
2011,国家自然科学基金青年项目,脊髓IL-33/ST2通路在大鼠关节炎痛中的作用及细胞分子机制,主持
2011,教育部博士点基金新教师基金项目,脊髓IL-33/ST2通路在电针缓解大鼠关节炎痛中的作用及细胞分子机制,主持
本科生课程:
中西医结合基础概论、疼痛生物医学、走近医学:历史与传承、疼痛:隐藏的慢性杀手、医学生综合素养、中西医学大师与人文素养
研究生课程:
医学研究生学习导引、神经科学原理、中西医结合基础概论、疼痛生物医学、疼痛研究技术与方法、慢性疼痛
2023-今 上海医学会疼痛学专科分会青年委员会副主任委员
2023-今 中国针灸学会针刺麻醉分会委员
2020-今 中国神经科学学会胶质细胞委员会委员
2020-今 中国中西医结合学会科研院所工作委员会委员
Chenghao Wang1, Hui He1, Tianchi Gao, Xinzheng Sun, Lixia Du, Yayue Yang, Jianyu Zhu, Yachen Yang, Yanqing Wang, Wenli Mi*. Analgesic Effect of Exercise on Neuropathic Pain via Regulating the Complement Component 3 of Reactive Astrocytes. Anesthesia & Analgesia. 2024 Jan 31.
Yayue Yang1, Lixia Du1, Jianyu Zhu, Ting Yi, Yachen Yang, Zheng Qiao, Qiliang Maoying, Yuxia Chu, Yanqing Wang, Wenli Mi*. Antipruritic effects of geraniol on acute and chronic itch via modulating spinal GABA/GRPR signaling. Phytomedicine. 2023, 119:154969.
Xinyi Gao1, Yayue Yang1, Jianyu Zhu, Yuxin Zhang, Chenghao Wang, Zhifei Wang*, Wenli Mi*, Lixia Du*. Xanthotoxol relieves itch in mice via suppressing spinal GRP/GRPR signaling. European Journal of Pharmacology. 2023, 960:176147.
Ling Xu1, Ming-Zhe Liu1, Ya-Yue Yang1, Yan Wang, Xiao-Xiao Hua, Li-Xia Du, Jian-Yu Zhu, Yang Shen, Yan-Qing Wang, Ling Zhang, Wen-Li Mi*, Di Mu*. Geraniol enhances inhibitory inputs to the paraventricular thalamic nucleus and induces sedation in mice, Phytomedicine, 2022, 153965.
Xue-Ming Hu1, Wei Yang1, Meng-Ting Zhang1, Li-Xia Du, Jia-He Tian, Jian-Yu Zhu, Yu Chen, Feng Hai, Shen-Bin Liu, Qi-Liang Mao-Ying, Yu-Xia Chu, Hong Zhou, Yan-Qing Wang, Wen-Li Mi*. Glial IL-33 signaling through an ST2-to-CXCL12 pathway in the spinal cord contributes to morphine-induced hyperalgesia and tolerance, Science signaling, 2021, 14(699): eabe3773.
Lixia Du, Xueming Hu, Wei Yang, Hanikezi Yasheng, Shenbin Liu, Wenwen Zhang, Yang Zhou, Wenqiang Cui, Jianyu Zhu, Zheng Qiao, Qiliang Maoying, Yuxia Chu, Hong Zhou, Yanqing Wang, Wenli Mi*. Spinal IL-33/ST2 signaling mediates chronic itch in mice through the astrocytic JAK2-STAT3 cascade. Glia. 2019 67(9):1680-1693.
Lixia Du, Yanqing Wang, Guoqiang Hua, Wenli Mi*. IL-33/ST2 Pathway as a Rational Therapeutic Target for CNS Diseases. Neuroscience 2018 369: 222–230.
Wenli Mi, Shuxing Wang, Zerong You, Grewo Lim, Michael F. McCabe, Hyangin Kim, Lucy Chen, Jianren Mao*. Nortriptyline Enhances Morphine-Conditioned Place Preference in Neuropathic Rats: Role of the Central Noradrenergic System. Anesthesia & Analgesia. 2017 125(3):1032-1041.
Shenbin Liu1, Qian Li1, Mengting Zhang, Qiliang Maoying, Langyue Hu, Gencheng Wu, Wen-Li Mi*, Yanqing Wang*. Curcumin ameliorates neuropathic pain by down-regulating spinal IL-1β via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling. Scientific Reports. 2016;6:28956.
Shenbin Liu1, Wenli Mi1, Qian Li, Mengting Zhang, Ping Han, Shan Hu, Qiliang Maoying, Yanqing Wang*. Spinal IL-33/ST2 signaling contributes to neuropathic pain via neuronal CaMKII-CREB and astroglial JAK2-STAT3 cascades in mice. Anesthesiology, 2015 123(5):1154-1169.
Ping Han1, Shenbin Liu1, Mengting Zhang1, Jing Zhao, Yanqing Wang, Gencheng Wu, Wenli Mi*. Inhibition of spinal Interlukin-33/ST2 signaling and downstream ERK and JNK pathways in electroacupuncture analgesia in formalin mice. PLOS ONE, 0129576, 12, 2015.
Ping Han, Jing Zhao, Shen-Bin Liu, Chang-Jiang Yang, Yan-Qing Wang, Gen-Cheng Wu, Da-Mo Xu, Wen-Li Mi*. Interleukin-33 mediates formalin-induced inflammatory pain in mice. Neuroscience, 2013 241:59-66.
Wen-Li Mi, Qi-Liang Mao-Ying, Xiao-Wei Wang, Xiu Li, Chang-Jiang Yang, Jian-Wei Jiang, Jin Yu, Jun Wang, Qiong Liu, Yan-Qing Wang*, Gen-Cheng Wu. Involvement of spinal neurotrophin-3 in the electroacupuncture analgesia and inhibition of spinal glial activation in rat model of monoarthritis. Journal of Pain. 2011 12(9):974-84.
一种简易型电动抚触装置 (已授权:ZL202223574272.1)
一种慢性瘙痒动物模型的制备器 (已授权:ZL201820822114.8)
抗ST2/IL-1 R4抗体在制备镇痛药物中的用途 (已授权:ZL201210517242.9)
抗ST2/IL-1 R4抗体在制备防治瘙痒药物中的应用 (已授权:ZL201210517244.8)